Evaluation of combination therapy using aciclovir and corticosteroid in adult patients with herpes simplex virus encephalitis
نویسندگان
چکیده
منابع مشابه
Evaluation of combination therapy using aciclovir and corticosteroid in adult patients with herpes simplex virus encephalitis.
OBJECTIVE Herpes simplex virus encephalitis (HSVE) is associated with significant morbidity and mortality, even with appropriate antiviral therapy. In the present investigation, the first to assess efficacy of corticosteroid treatment with aciclovir therapy in HSVE, multiple logistic regression analysis was performed of predictors of outcome in adult patients with HSVE. METHODS A non-randomis...
متن کاملTherapy of experimental herpes simplex encephalitis with aciclovir in mice.
This report is concerned with the capacities of aciclovir to protect mice challenged intracerebrally with multiple lethal doses of type 1 herpes simplex virus and to control multiplication of this virus in the brain. With treatment initiated 12 h after inoculation and continued for 4 consecutive days, aciclovir administered subcutaneously in daily doses ranging from 40 to 100 mg/kg led to 21-da...
متن کاملAnalysis of Herpes Simplex Virus in Suspected Encephalitis, Keratitis and Dermal Infections Using Real- Time PCR
Background & Objectives: Herpes viruses can cause diseases in the clinical range. The virus can cause infection in various body parts, especially eyes and nervous system. The aim of this study was at evaluating the Real-Time TaqMan probe PCR in diagnosing and monitoring of the patients with suspected HSV infections.Materials & Methods: More than a thousand patients with suspected HSV infection...
متن کاملHerpes simplex virus encephalitis.
Introduction Herpes simplex virus encephalitis is one of the more common sporadic viral encephalitides with an estimated incidence of one case per half million individuals per year (1, 2), but the true incidence may be higher. Untreated it is associated with a mortality rate exceeding 70070 and a high morbidity amongst the survivors with only about 9070 returning to normal neurological function...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 2005
ISSN: 0022-3050
DOI: 10.1136/jnnp.2004.049676